- Saad
- Saenz
- Sahawneh
- Sakmar
- Salant
- Salchert
- Salmon
- Salter
- Salze
- Sample
- Sampson
- Samuels
- Sanders
- Sanderson
- Sandidge
- Sandlin
- Sanford
- Santini
- Sarno
- Sarris
- Satisfield
- Satterwhite
- Saunders
- Savage
- Sawyer
- Saxon
- Saxton
- Scaife
- Scales
- Scalici
- Scarborough
- Scarbrough
- Scarpulla
- Schaper
- Schapmann
- Scharf
- Scheinert
- Scheirer
- Scherer
- Scheuermann
- Schifanella
- Schifano
- Schiffanella
- Schillie
- Schimzzi
- Schmidt
- Schmitz
- Schmuck
- Schneider
- Schnell
- Schnepp
- Schober
- Schoettlin
- Scholl
- Schuelly
- Schuessler
- Schulman
- Schuster
- Sciarabba
- Sciascia
- Scott
- Scripps
- Scroggins
- Scruggs
- Seaborn
- Seaman
- Searight
- Sears
- Seay
- Secord
- Sefton
- Segars
- Seigel
- Seitz
- Selden
- Self
- Selle
- Sellers
- Seltzer
- Seng
- Senkbeil
- Sentenn
- Seright
- Sertell
- Sessamen
- Sewell
- Seymour
- Shackelford
- Shackford
- Shaffer
- Shah
- Shalhoop
- Shaneyfelt
- Shanklin
- Shannon
- Sharlach
- Sharp
- Sharpe
- Sharpton
- Shaver
- Shaw
- Shay
- Shearer
- Sheffield
- Shehadeh
- Shell
- Shelley
- Shelnutt
- Shelton
- Shepherd
- Sheppard
- Sherer
- Sheriff
- Sherk
- Sherman
- Shern
- Sherrill
- Shields
- Shihaee
- Shilkrot
- Shine
- Shiplet
- Shipp
- Shirah
- Shirley
- Shivers
- Shoemaker
- Shores
- Short
- Shorts
- Shoultz
- Shu
- Shuler
- Shunnarah
- Shuttleworth
- Sicola
- Sides
- Siegal
- Siegwart
- Sikora
- Silins
- Sills
- Silmon
- Sim
- Simmons
- Simon
- Simonetti
- Simpkins
- Simpson
- Sims
- Singleton
- Sisson
- Skaggs
- Skanes
- Skelton
- Skinner
- Skipper
- Slaughter
- Slawson
- Slay
- Sledge
- Slimp
- Sloneker
- Small
- Smallwood
- Smedley
- Smeraglia
- Smiley
- Smith
- Snead
- Snider
- Snipe
- Snoddy
- Snow
- Snyder
- Sojourner
- Sokol
- Soles
- Sollack
- Solmon
- Solomon
- Sottilare
- Sousa
- Soverow
- Sparks
- Spates
- Speanburg
- Spearman
- Spears
- Speck
- Speed
- Speer
- Speight
- Spencer
- Sperando
- Sperling
- Spiegner
- Spiker
- Spikes
- Spina
- Spivak
- Spivey
- Splawn
- Springer
- Springfield
- Sproull
- Spurlock
- Square
- Sridhar
- Stahlhut
- Stallings
- Stallworth
- Stamm
- Stanaland
- Standifer
- Stanfield
- Stanley
- Stansel
- Stanton
- Starks
- Startley
- Statham
- Staub
- Staula
- Stave
- Stayer
- Stearns
- Steber
- Steed
- Steedman
- Steele
- Steeley
- Stegall
- Stephens
- Stephenson
- Steul
- Steve
- Stevens
- Stevenson
- Steward
- Stewart
- Stiff
- Stiffler
- Stimpson
- Stine
- Stinson
- Stoessel
- Stofan
- Stokes
- Stollenwerck
- Stone
- Stonecypher
- Stoner
- Stoney
- Storey
- Stoudemire
- Stough
- Stovall
- Stover
- Stowe
- Stracener
- Stracner
- Straeter
- Strait
- Straka
- Strange
- Streeter
- Strickland
- Stricklin
- Stringfellow
- Stripling
- Strode
- Strotter
- Stroud
- Stroup
- Strouss
- Struck
- Stuart
- Stubblefield
- Stuckey
- Studencki
- Studimire
- Sturdivant
- Sturgeon
- Styslinger
- Sudduth
- Sullins
- Sullivan
- Sumlin
- Summerville
- Sumner
- Sumners
- Sumpter
- Sundock
- Sutley
- Sutliffe
- Suttles
- Sutton
- Swaffield
- Swafford
- Swaim
- Swain
- Swanger
- Swann
- Swanson
- Swart
- Swartz
- Sweat
- Swinford
- Swope
- Sykes
- Sywy
- Syx
- Szczuka